Eastern Conference
| # | Team | P | W | D | L | GF | GA | GD | Pts | Last Results | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Philadelphia Union | 29 | 17 | 6 | 6 | 49 | 26 | 23 | 57 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 2 | FC Cincinnati | 29 | 16 | 4 | 9 | 42 | 36 | 6 | 52 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 3 | Charlotte | 29 | 16 | 2 | 11 | 48 | 40 | 8 | 50 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 4 | Nashville SC | 29 | 15 | 5 | 9 | 49 | 33 | 16 | 50 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 5 | Orlando City SC | 28 | 13 | 8 | 7 | 54 | 40 | 14 | 47 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 6 | Inter Miami | 25 | 13 | 7 | 5 | 54 | 40 | 14 | 46 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 7 | Columbus Crew | 28 | 12 | 10 | 6 | 43 | 39 | 4 | 46 | Promotion - MLS (Play Offs: 1/8-finals) | |
| 8 | New York City FC | 27 | 13 | 5 | 9 | 38 | 32 | 6 | 44 | Promotion - MLS (Play Offs: 1/16-finals) | |
| 9 | New York Red Bulls | 29 | 11 | 7 | 11 | 42 | 38 | 4 | 40 | Promotion - MLS (Play Offs: 1/16-finals) | |
| 10 | Chicago Fire | 27 | 11 | 6 | 10 | 50 | 48 | 2 | 39 | ||
| 11 | New England Revolution | 28 | 8 | 7 | 13 | 36 | 40 | -4 | 31 | ||
| 12 | Atlanta United FC | 28 | 5 | 11 | 12 | 32 | 49 | -17 | 26 | ||
| 13 | Toronto FC | 28 | 5 | 10 | 13 | 28 | 35 | -7 | 25 | ||
| 14 | CF Montreal | 29 | 5 | 9 | 15 | 29 | 51 | -22 | 24 | ||
| 15 | DC United | 29 | 5 | 9 | 15 | 26 | 54 | -28 | 24 |